Assay 01 · sequence-context multiple choice

Consequence classification

Predict the Ensembl VEP most severe consequence for a human GRCh38 SNV using only its centered local sequence window and variant alleles.

Task design

questions

10 per consequence class

consequence classes

balanced development set

1,001 bp window

variant centered at position 501

Exact-match scoring

last valid FINAL line

Model-visible inputs

Reference
Homo sapiens GRCh38
Region
Chromosome 17
Variant
Centered SNV in local VCF
VEP
release 109.1
Flags
--most_severe --distance 1000

Interpretation

Task version
1.1
Questions
Public development set
Annotations
Transcript annotations intentionally omitted
Collapsed class
Intergenic, intronic, upstream, and downstream
Explorer
Static; no backend or hidden state

Results and records

Browse the current task questions, optionally with the predictions from a complete committed evaluation run. Select one row to inspect the full model-visible prompt and observed response.

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